FIELD: chemistry.
SUBSTANCE: described are spirocyclic derivatives of cyclohexane of general formula 
. Values of radicals are given in the formula of invention. The compounds have affinity to the ORL1 receptor and can be used for treating abstinence syndrome (withdrawal syndrome) and pain. Also described is a medicinal agent and use of formula (I) compounds for preparing respective medicinal agents.
EFFECT: increased effectiveness of using the compounds.
13 cl, 17 ex, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| SPIROCYCLIC CYCLOHEXANE DERIVATIVES | 2003 |
|
RU2354656C2 |
| SPIROCYCLIC AZAINDOLE DERIVATIVES | 2007 |
|
RU2468028C2 |
| SPIROCYCLIC CYCLOHEXANE DERIVATIVES | 2008 |
|
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|
RU2592283C2 |
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|
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| SPIRO(5,5)UNDECANE DERIVATIVES | 2009 |
|
RU2515895C2 |
| HYDROXYMETHYL CYCLOHEXYLAMINES | 2009 |
|
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| SUBSTITUTED DERIVATIVES OF 4-AMINOCYCLOHEXANOL, METHOD FOR THEIR PREPARING AND THEIR USING, MEDICINAL AGENT POSSESSING BINDING PROPERTY WITH ORL1-RECEPTOR | 2002 |
|
RU2315750C2 |
| SUBSTITUTED DERIVATIVES OF 2-PYRIDINCYCLOHEXANE-1,4-DIAMINE, METHOD FOR THEIR PREPARING AND MEDICINAL AGENT BASED ON THEREOF | 2002 |
|
RU2287523C2 |
| SUBSTITUTED DERIVATIVES OF CYCLOHEXAN-1,4-DIAMINE, METHOD FOR THEIR PREPARING AND DRUG | 2002 |
|
RU2321579C2 |
