SPIROCYCLIC CYCLOHEXANE DERIVATIVES Russian patent published in 2013 - IPC C07D471/10 C07D491/107 C07D495/10 A61K31/407 A61P25/00 

Abstract RU 2484092 C2

FIELD: chemistry.

SUBSTANCE: invention relates to spirocyclic cyclohexane derivatives of formula I where values of R1-10 are given in claim 1.

EFFECT: compounds have affinity for the ORL1 receptor, which enables use thereof in producing a medicinal agent for treating pain, especially sharp, neuropathic or chronic pain.

12 cl, 1 tbl, 52 ex

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RU 2 484 092 C2

Authors

Shunk Shtefan

Tsemol'Ka Zaskia

Sonders Derek

Gruss Mikhaehl'

Graubaum Khajnts

Dates

2013-06-10Published

2008-02-19Filed