FIELD: chemistry.
SUBSTANCE: invention relates to spirocyclic cyclohexane derivatives of formula I where values of R1-10 are given in claim 1.
EFFECT: compounds have affinity for the ORL1 receptor, which enables use thereof in producing a medicinal agent for treating pain, especially sharp, neuropathic or chronic pain.
12 cl, 1 tbl, 52 ex
Title | Year | Author | Number |
---|---|---|---|
SPIROCYCLIC AZAINDOLE DERIVATIVES | 2007 |
|
RU2468028C2 |
SPIROCYCLIC CYCLOHEXANE DERIVATIVES | 2008 |
|
RU2470933C2 |
SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | 2009 |
|
RU2503660C2 |
SUBSTITUTED DERIVATIVES OF 4-AMINOCYCLOHEXANE | 2009 |
|
RU2532545C2 |
SPIRO(5,5)UNDECANE DERIVATIVES | 2009 |
|
RU2515895C2 |
DISPIROPYRROLIDINE DERIVATIVES | 2012 |
|
RU2612534C2 |
BICYCLIC LACTAMS AND METHODS FOR USE THEREOF | 2016 |
|
RU2716136C2 |
HYDROXYMETHYL CYCLOHEXYLAMINES | 2009 |
|
RU2514192C2 |
5-SUBSTITUTED INDAZOLE AS KINASE INHIBITORS | 2008 |
|
RU2487873C2 |
DERIVATIVES OF 2-(PYRANO[3,2-C]CHROMEN-5-YL)ACETIC ACID AND METHOD FOR THEIR PREPARATION | 2021 |
|
RU2775546C1 |
Authors
Dates
2013-06-10—Published
2008-02-19—Filed