SPIROCYCLIC AZAINDOLE DERIVATIVES Russian patent published in 2012 - IPC C07D491/147 C07D495/14 A61K31/436 A61K31/437 A61P25/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel spirocyclic azaindole derivatives of formula I: , where: one of A stands for N, and the other ones stand for CR^7-10; W stands for NR⁴; X stands for O, S; R¹ and R², independently on each other stand for H; C_1-5-alkyl each time saturated, branched or unbranched, non-substituted or monosubstituted with -OC_1-6alkyl; phenyl, thienyl, morpholinyl, benzothiophenyl or benzodioxilyl, each time non-substituted or monosubstituted with F, C_1-6alkyl; or 5-membered heteroaryl, containing three nitrogen atoms as heteroatoms, substituted with C_1-3alkyl; bound with C_1-3-alkyl group phenyl non-substituted or monosubstituted with F or C_1-6alkyl; R⁴ stands for H; R⁵ stands for H; R⁶ stands for H; R⁷, R⁸, R⁹ and R¹⁰ stand for H or CP₃; in form of siastereomers, mixtures of diastereomers or separate diastereomer; bases and/or salts of physiologically compatible acids. Compounds are suitable for treatment of a number of diseases, for instance, pain, stress, depressions, etc. Described is method of their obtaining.

EFFECT: compounds are suitable for treatment of a number of diseases, for instance, pain, stress, depressions.

11 cl; 1 tbl; 34 ex