FIELD: chemistry.
SUBSTANCE: invention relates to the novel compounds with formula (I):
where R1 is (C2-4)alkyl and is substituted with two or more fluorine groups; and R2 is methyl or ethyl; or to pharmaceutically acceptable salts thereof. The invention also relates to a method of obtaining formula (I) compounds, to a pharmaceutical composition, to use of the compounds, as well as to a method of inhibiting collagenase-3 activity.
EFFECT: obtaining new biologically active compounds having inhibitory effect on collagenase-3.
13 cl, 12 ex, 1 tbl
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