FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new compounds of formula (I) as (S)-stereoisomers or to their pharmaceutically acceptable salts which exhibit properties of MMP12 or MMP9 inhibitor. In formula (I) , R1 represents C1-2alkyl, cyclopropyl, OCH3 or SCH3, and said alkyl group is optionally substituted with one or more than one fluorine atom, and R2 represents C1-2alkyl.
EFFECT: invention also refers to methods for making compounds of formula (I), to the pharmaceutical composition and the method for making thereof, and also to application of the compounds of formula (I).
17 cl, 1 tbl, 6 ex
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Authors
Dates
2010-04-20—Published
2005-07-04—Filed