NEW HYDANTOIC DERIVATIVES FOR TREATING OBSTRUCTIVE AIRWAY DISEASES Russian patent published in 2010 - IPC C07D401/14 A61K31/506 A61P11/00 

Abstract RU 2386629 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new compounds of formula (I) as (S)-stereoisomers or to their pharmaceutically acceptable salts which exhibit properties of MMP12 or MMP9 inhibitor. In formula (I) , R1 represents C1-2alkyl, cyclopropyl, OCH3 or SCH3, and said alkyl group is optionally substituted with one or more than one fluorine atom, and R2 represents C1-2alkyl.

EFFECT: invention also refers to methods for making compounds of formula (I), to the pharmaceutical composition and the method for making thereof, and also to application of the compounds of formula (I).

17 cl, 1 tbl, 6 ex

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RU 2 386 629 C2

Authors

Gabos Balint

Ripa Lena

Stenvall' Kristina

Dates

2010-04-20Published

2005-07-04Filed