N-OXIDES AS PRODRUG OF PIPERAZINE AND PIPERIDINE DERIVATIVES Russian patent published in 2010 - IPC C07D263/58 C07D295/24 A61K31/423 A61P25/00 

Abstract RU 2394821 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel piperazine derivatives of formula (I) , where Q is methyl, benzyl or (1,1'-biphenyl)-3-ylmethyl, and pharmacologically acceptable salts thereof. The invention also relates to a pharmaceutical composition, to a method of preparing pharmaceutical compositions, to use of the compounds, as well as to a method of producing the compounds.

EFFECT: obtaining novel biologically active compounds with partial or complete agonist effect on dopamine D2 and 5-HT1A receptors.

9 cl, 6 ex, 1 tbl

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RU 2 394 821 C2

Authors

Kopman Teodorus S. M.

Koster Khendrik J.

Van Amsterdam Peter Kh.

Fenstra Rulof V.

Verage Marinus

Makkriri Ehndrju K.

Khesselink Majke B.

Van Skharrenburg Gustaf J. M.

Dates

2010-07-20Published

2006-08-21Filed