HIV-INHIBITING 2-(4-CYANOPHENYLAMINO)-PYRIMIDINE-OXIDE DERIVATIVES Russian patent published in 2010 - IPC C07D239/48 A61K31/505 A61P31/18

Abstract RU 2398768 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new 2-(4-cyanophenylamino)-pyrimidine-oxide derivatives exhibiting activity with respect to HIV of formula (I): , where R¹ represents bromine atom; each R² and R³ independently from each other represents C_1-6-alkyl, and also to their pharmaceutically acceptable additive salts. The invention also concerns a pharmaceutical composition and a method of preparing a pharmaceutical composition.

EFFECT: preparation of new 2-(4-cyanophenylamino)-pyrimidine-oxide derivatives exhibiting activity with respect to HIV.

4 cl, 7 dwg, 1 tbl, 3 ex

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RU 2 398 768 C2

Authors

De Kok Kherman Augustinus

Vigerink Pit Tom Bert Pol'

Dates

2010-09-10—Published

2006-02-20—Filed