METHOD OF DETERMINING TACTICS OF TREATING LOCALLY ADVANCED AND DISSEMINATED RENAL CELL CARCINOMA Russian patent published in 2010 - IPC A61K38/20 A61K38/21 A61K31/675 A61K31/7068 A61P35/00 

Abstract RU 2403056 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to oncology, and can be used in treatment of locally advanced and disseminated renal cell carcinoma. Method includes determination of absolute concentration of cells with phenotypes CD57+ in mm (X5) and CD4+CD25+Treg in mm3 (X4), as well as levels of spontaneous production of interleukine-6 in pg/ml (X3), interleukine-8 in pg/ml (X2) and interferon-γ in pg/ml (XI). Obtained data are used to calculate discriminant functions and the largest value of the function is used to predict patient's life duration and to administer treatment depending on predicted life duration.

EFFECT: application of invention allows to carry out adequate treatment of patients with different life duration, to optimise regimens of medication introduction, to improve remote results of treatment of patients with disseminated and locally advanced renal cell carcinoma.

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Authors

Granov Anatolij Mikhajlovich

Molchanov Oleg Evgen'Evich

Karelin Mikhail Ivanovich

Shkol'Nik Mikhail Iosifovich

Dates

2010-11-10Published

2009-06-16Filed