OPHTHALMIC COMPOSITIONS AND METHODS OF TREATING EYES Russian patent published in 2011 - IPC A61K9/08 A61K31/221 A61P27/02 

Abstract RU 2410081 C2

FIELD: medicine.

SUBSTANCE: ophthalmic composition contains a water carrier ingredient and an effective amount of at least one compatible soluble substance for eye surface protection against hyperosmotic stress where the compatible soluble substance is chosen from a group consisting of carnitine and erythrite. The ophthalmic composition has osmolarity in the range 200 to 1000 mOsmol/kg. Also, the ophthalmic composition can contains glycerine and carboxymethyl cellulose, a preserving agent. The ophthalmic composition delivers compatible soluble substances to eye surface cells to counterbalance an osmotic stress thereon. The composition is applied for manufacturing a drug for eye surface protection against hyperosmotic stress. A method of treating human dry eye keratitis involves administration of said composition.

EFFECT: eye protection in adverse effect of cationic compounds on the eye surface and simplified process of eye restoration following a surgical intervention.

13 cl, 7 tbl, 8 dwg, 20 ex

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RU 2 410 081 C2

Authors

Veidzh Dzhozef Dzh.

Simmons Piter A.

Cheng-Lin Dzhoan-Ehn

Dates

2011-01-27Published

2005-11-14Filed