FIELD: biotechnology.
SUBSTANCE: method for production of modified purine nucleosides of β-D-arabinofuranose series. The method is implemented by reacting a purine ribonucleoside with 1-β-D-arabinofuranosyluracil or 1-α-phosphate of D-arabinose in a potassium phosphate buffer in the presence of purine nucleoside phosphorylase or a mixture of purine and pyrimidine nucleoside phosphorylases in the presence of ortho-arsenic acid salts.
EFFECT: simplification of the technique of β-D-arabinofuranose series modified purine nucleosides production from natural or chemically modified β-D-ribofuranose nucleosidesβ.
1 tbl, 16 dwg, 11 ex
| Title | Year | Author | Number |
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| METHOD OF PRODUCING 9-(BETA-D-ARABINOFURANOSYL)-6-(N-L-SERYLAMIDO)-2-CHLOROPURINE | 2014 |
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| MIMETICS OF POLY (ADP-RIBOSE) AND PROCESS FOR PRODUCING THEREOF | 2011 |
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| METHOD OF SYNTHESIS OF 2'-DEOXY-2'-FLUORORIBONUCLEOSIDE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1990 |
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