SALTS OF PIPERAZINE DERIVATIVE WITH SALICYLIC AND GENTISIC ACID Russian patent published in 2011 - IPC C07D413/12 C07C65/05 A61K31/538 A61P25/18 

Abstract RU 2412184 C2

FIELD: chemistry.

SUBSTANCE: invention describes compounds of formula 2 and 3

, synthesis methods thereof, pharmaceutical compositions, as well as use thereof to prepare a medicinal agent, having antagonistic activity towards D2-receptors and modulating activity towards 5HT reuptake.

EFFECT: present invention provides salt forms used as modulators of one or more GPCR.

20 cl, 3 tbl, 5 dwg, 4 ex

Similar patents RU2412184C2

Title Year Author Number
-E-10-OH-NT COMPOSITIONS AND METHOD FOR SYNTHESIS AND USE THEREOF 2008
  • Le Burdonnek Bertran
  • Doll Roland
RU2469715C2
SOLID FORMS CONTAINING (-)-O-DESMETHYLVENLAFAXINE AND USE THEREOF 2008
  • Sizenski Majkl
  • Uilkinson Kharold S.
  • Snunian Dzhon
  • Kim Norman
  • Laflin Sharon M.
  • Bekejl Rodzher P.
  • Plankett Kevin
  • Mauso Patrik
RU2477269C2
SUBSTITUTED 6-(1-PIPERAZINYL)-PYRIDAZINES AS 5-HT6 RECEPTOR ANTAGONISTS 2009
  • Bartolome-Nebreda Khose Manuehl'
  • Makdonal'D Gregor Dzhejms
  • Van Gol Mikhil' Ljuk Marija
  • Konde-Sejde Susana
  • Del'Gado-Khimenes Fransiska
RU2502734C2
PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OR PREVENTION OF DISORDER OF CENTRAL NERVOUS SYSTEM 2017
  • Yao, Wei
  • Li, Peng
RU2776800C2
CHIMERIC POLYPEPTIDE SELECTIVELY REACTING WITH RELATED CHEMOKINE RECEPTOR, PHARMACEUTICAL COMPOSITION AND APPLICATION OF CHIMERIC POLYPEPTIDE (VERSIONS) 2005
  • Kuliopulos Atan
  • Kovik Lidija
  • Kanajder Nikol'
RU2430113C2
ORGANIC COMPOUNDS 2017
  • Yao, Wei
  • Li, Peng
RU2743513C2
NOVEL FUMARATE SALTS OF H3 HISTAMINE RECEPTOR ANTAGONISTS 2010
  • Landzhevin Beverli S.
  • Farr Robert Allan
  • Shakh Dinubkhaj Kh.
  • Sherer Daniehl'
RU2537847C2
1,2,4-TRIAZOLO[4,3-A]PYRIDINE COMPOUNDS AND USE THEREOF AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS 2015
  • Cid-Nunez Jose Maria
RU2695651C2
VORTIOXYETINE PYROGLUTAMATE 2016
  • De Diego, Heidi, Lopez
  • Christensen, Kim, Lasse
  • Holm, Rene
  • Kateb, Jens
RU2713889C2
LIGAND WITH WIDE RANGE OF SIMULTANEOUS RECEPTOR ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD OF PREPARING SAID COMPOSITION AND MEDICINAL AGENT 2008
  • Ivashchenko Aleksandr Vasil'Evich
  • Ivashchenko Andrej Aleksandrovich
  • Savchuk Nikolaj Filippovich
RU2374245C1

RU 2 412 184 C2

Authors

Deshmukkh Subodkh S.

Ali Kadum

Dajorio Kristofer R.

D'Julin Uehndi

Ehrnsperdzher Ehrik S.

Favzi Makhdi B.

Shakh Sied Muzafar

Dates

2011-02-20Published

2006-09-12Filed