FIELD: medicine.
SUBSTANCE: chimeric polypeptide contains a first domain which is a first intracellular loop (i1-loop) of chemokine receptor, and a second domain coupled with the first domain where the second domain is a cell-penetrating and membrane-bound natural or artificial hydrophobic residue. The produced polypeptide is used in treating a disease or a condition characterised by pathological activity of chemokine receptor.
EFFECT: invention enables producing chimeric polypeptide which is selectively reacting with related chemokine receptor.
13 cl, 33 dwg, 3 tbl, 15 ex
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