PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OR PREVENTION OF DISORDER OF CENTRAL NERVOUS SYSTEM Russian patent published in 2022 - IPC C07D471/16 A61K31/4985 A61K31/445 A61P25/00 

FIELD: medicine; neurology; psychiatry.

SUBSTANCE: claimed group of inventions relates to the field of medicine, namely neurology and psychiatry, and discloses a pharmaceutical composition for the treatment of a disorder of the central nervous system, containing therapeutically effective amount of a compound of the Formula I, in which: X is -NH-; L is O; Z is -O-; in free or a pharmaceutically acceptable salt form, mixed with a pharmaceutically acceptable diluent or carrier; where the specified disorder of the central nervous system is a disorder related to the substance use, or a disorder caused by the substance use, where the specified disorder related to the substance use, or disorder caused by substance use affects the mu-opioid receptor. The group of inventions also relates to a method for the treatment or prevention of a disorder of the central nervous system.

EFFECT: obtained pharmaceutical compositions are suitable for the treatment of a disorder of the central nervous system, where the specified disorder of the central nervous system is a disorder related to the substance use, or a disorder caused by the substance use, where the specified disorder related to the substance use, or disorder caused by the substance use affects the mu-opioid receptor.

Formula I

14 cl, 8 ex