FIELD: medicine.
SUBSTANCE: invention refers to medicine and concerns composites for waxed reconstruction of the injured bone tissues. High-porous elastic chitosan-gelatin matrixes of porosity 90 % or more consist of chitosan and contain gelatin up to 60 wt % and sodium lauryl sulphate up to 0.2-0.4 wt %. The porous structure is produced by introducing the additives, freezing and sublimation drying.
EFFECT: due to elasticity and high porosity, said sponges fill bone defects with a minimum clearance that promotes the uniform formation of bone tissue throughout the defect; high solubility of matrixes provides fast bone tissue genesis.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| POROUS COMPOSITE CHITOSAN AND GELATIN-BASED MATERIAL FOR FILLING IN BONE DEFECTS | 2009 |
|
RU2412711C1 |
| POROUS COMPOSITE MATERIALS BASED ON CHITOSAN FOR FILLING OF BONE DEFECTS | 2007 |
|
RU2376019C2 |
| METHOD OF OBTAINING POROUS CHITOSAN CALCIUM PHOSPHATE-CONTAINING SPONGES FOR FILLING BONE DEFECTS | 2014 |
|
RU2554811C1 |
| BIORESORBABLE BARRIER MEMBRANE BASED ON POLYSACCHARIDE FOR DIRECTED REGENERATION OF BONE TISSUE | 2019 |
|
RU2713657C1 |
| METHOD FOR MAKING POROUS CHITOSAN SPONGES FOR BONE DEFECT FILLING | 2007 |
|
RU2356581C1 |
| METHOD FOR PREPARING CALCIUM PHOSPHATE COMPOSITE | 2014 |
|
RU2554804C1 |
| METHOD OF NANOCOMPOSITE PRODUCTION FOR BONE TISSUE REGENERATION | 2019 |
|
RU2715338C1 |
| METHOD OF PRODUCING COMPOSITE 3D FRAME FOR REPLACEMENT OF BONE-CARTILAGE DEFECTS | 2015 |
|
RU2606041C2 |
| BIOACTIVE RESORBED POROUS 3D-MATRIX FOR REGENERATIVE MEDICINE AND METHOD FOR PREPARING IT | 2013 |
|
RU2533457C1 |
| METHOD OF PRODUCTION OF POROUS CERAMIC GRANULES ON BASIS OF CALCIUM CARBONATE AND HYDROXYAPATITE AND/OR CARBONATE HYDROXYAPATITE FOR FILLING OF BONE DEFECTS AT RECONSTRUCTIVE PLASTIC SURGERIES | 2014 |
|
RU2555348C1 |
