COMPOSITE MATERIAL CONTAINING SODIUM ALGINATE AND MIXTURE OF CALCIUM PHOSPHATES, METHOD OF PRODUCING COMPOSITE MATERIAL Russian patent published in 2020 - IPC A61L27/00 A61L27/12 A61L27/32 C04B35/447 C01B25/32 

Abstract RU 2725882 C1

FIELD: medicine.

SUBSTANCE: invention relates to production of new composite materials for medicine, namely traumatology and orthopedics, maxillofacial surgery and surgical dentistry, and can be used for production of composite materials intended for filling of bone defects. Disclosed is a composite material containing sodium alginate and a mixture of calcium phosphates, characterized by the following ratio of components, wt. %: sodium alginate - 90÷80, mixture of calcium phosphates - 10÷20. Sodium alginate is 2 % aqueous suspension, and the total weight of the mixture of calcium phosphates contains: hydroxyapatite (HA) - 20 %, brushite - 30 %, octacalcium phosphate (OCP) - 50 %. Method of producing said composite material involves preliminary preparation of 2 % aqueous suspension of sodium alginate, adding to the resulting suspension a powder mixture of calcium phosphates in the form of HA - 20 %, brushite - 30 %, OCP - 50 % in amount of 10÷20 wt. % of total weight of composite material, mixing during time T1 = 10÷15 min by means of magnetic mixer and foaming. Then, the foam is put into the crucible and dried at temperature of 200 °C for time T2 = 20÷30 minutes.

EFFECT: technical result is obtaining a more bioresorbable and porous material.

2 cl, 1 tbl, 4 dwg

Similar patents RU2725882C1

Title Year Author Number
COMPOSITE MATERIAL FOR FILLING BONE DEFECTS, CONTAINING AN ALGINATE-CHITOSAN POLYELECTROLYTE COMPLEX 2020
  • Golovanova Olga Aleksandrovna
  • Tsyganova Anna Anatolevna
RU2765546C1
METHOD OF PREPARING MIXTURE FOR PRODUCING CERAMIC BIODEGRADABLE MATERIAL 2010
  • Putljaev Valerij Ivanovich
  • Safronova Tat'Jana Viktorovna
  • Kukueva Elena Vjacheslavovna
  • Tret'Jakov Jurij Dmitrievich
RU2456253C2
HYDROGEL FOR PRODUCTION OF COMPOSITE MATERIALS WITH ANTIBACTERIAL ACTIVITY FOR OSTEOCHONDRAL DEFECTS SUBSTITUTION BY 3D-PRINTING METHOD 2016
  • Komlev Vladimir Sergeevich
  • Sergeeva Natalya Sergeevna
  • Fedotov Aleksandr Yurevich
  • Teterina Anastasiya Yurevna
  • Barinov Sergej Mironovich
  • Sviridova Irina Konstantinovna
  • Tyutkova Yuliya Borisovna
  • Karalkin Pavel Anatolevich
  • Kirsanova Valentina Aleksandrovna
  • Kuvshinova Ekaterina Alekseevna
  • Kaprin Andrej Dmitrievich
RU2632431C2
COMPOSITE CALCIUM PHOSPHATE CEMENT FOR BONE GRAFTING 2014
  • Grishchenko Dina Nikolaevna
  • Medkov Mikhail Azar'Evich
  • Djujzen Inessa Valer'Evna
  • Shulepin Ivan Vladimirovich
RU2554769C1
METHOD OF PRODUCING POWDERED MATERIAL BASED ON CARBONATED HYDROXYAPATITE AND BRUSHITE 2014
  • Solonenko Anna Petrovna
  • Golovanova Ol'Ga Aleksandrovna
RU2546539C1
METHOD TO PREPARE CHARGE TO PRODUCE BIOCERAMICS 2009
  • Safronova Tat'Jana Viktorovna
  • Putljaev Valerij Ivanovich
  • Reshotka Dar'Ja Sergeevna
  • Lukin Evgenij Stepanovich
  • Tret'Jakov Jurij Dmitrievich
RU2431627C2
BIOACTIVE COMPOSITE MATERIAL FOR BONE DEFECT REPLACEMENT AND METHOD FOR ITS MANUFACTURE 2016
  • Guzeev Vitalij Vasilevich
  • Guzeeva Tatyana Ivanovna
  • Zelichenko Elena Alekseevna
  • Gurova Oksana Aleksandrovna
  • Nesterenko Andrej Aleksandrovich
RU2617050C1
METHOD OF PRODUCING COMPOSITE MATERIAL FOR BONE DEFECT REPLACEMENT WITH HELP OF HYDROLYTIC CONVERSION 2015
  • Filippov Yaroslav Yurevich
  • Safronova Tatyana Viktorovna
  • Putlyaev Valerij Ivanovich
  • Larionov Dmitrij Sergeevich
  • Kovalkov Valerij Konstantinovich
  • Sokolov Andrej Vladimirovich
RU2599022C1
METHOD FOR PREPARING CALCIUM PYROPHOSPHATE POROUS CERAMICS 2012
  • Safronova Tat'Jana Viktorovna
  • Putljaev Valerij Ivanovich
  • Filippov Jaroslav Jur'Evich
  • Larionov Dmitrij Sergeevich
  • Averina Alena Evgen'Evna
  • Ivanov Vladimir Konstantinovich
RU2531377C2
METHOD OF PRODUCING COMPOSITE 3D FRAME FOR REPLACEMENT OF BONE-CARTILAGE DEFECTS 2015
  • Komlev Vladimir Sergeevich
  • Fedotov Aleksandr Yurevich
  • Teterina Anastasiya Yurevna
  • Zobkov Yurij Valerevich
  • Tyutkova Yuliya Borisovna
  • Barinov Sergej Mironovich
  • Sergeeva Natalya Sergeevna
  • Sviridova Irina Konstantinovna
  • Kirsanova Valentina Aleksandrovna
RU2606041C2

RU 2 725 882 C1

Authors

Golovanova Olga Aleksandrovna

Tsyganova Anna Anatolevna

Dates

2020-07-07Published

2019-05-06Filed