SOVIALEM ALBUMIN MODIFICATION AS METHOD FOR STABILITY ENHANCEMENT FOR PREPARING PHARMACEUTICAL BIOLOGICAL PREPARATION OF ALBIMUN IN COMPLEX WITH GENTAMYCIN OR STIMADEN Russian patent published in 2011 - IPC A61K38/38 A61P31/04 A61P37/02 

Abstract RU 2414237 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine and concerns a method for albumin stabilisation for preparing based pharmaceutical biological preparations with additional antibiotic (gentamycin) or immunomodulating (stimadene) with mechanisms of action by sovialem protein modification.

EFFECT: invention provides higher stability of copolymer modified forms of albumin to physical (60°C, 10 hours) and chemical (gentamycin, stimadene) actions with an evident protein- denaturing effect.

2 cl, 1 ex, 1 dwg, 5 tbl

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RU 2 414 237 C2

Authors

Barsukov Aleksej Konstantinovich

Nesterova Ol'Ga Jur'Evna

Kasimov Fljur Minisalikhovich

Kozhevnikova Ol'Ga Vladimirovna

Kuznetsov Aleksandr Ivanovich

Ushnurtseva Svetlana Aleksandrovna

Panarin Evgenij Fedorovich

Gavrilova Irina Iosifovna

Dates

2011-03-20Published

2008-04-30Filed