FIELD: medicine.
SUBSTANCE: for simulating a combined radiation mechanical injury, animals are exposed to whole-body homogeneous irradiation in a dose that invokes development of acute moderate radiation sickness. It is followed with consistent mechanical injuring to simulate a moderate or severe closed abdominal injury involving a spleen with a load 0.5 kg, falling under its own weight of own weight from height 1 m in a hollow drive pipe fixed in a support at an angle 75°. The animals are fixed lying flat on the back and turned right-side Thereafter, developing life dangerous consequences represented by continuous abdominal hemorrhage and traumatic shock signs burdened by symptoms of a primary radiation response are stated to start urgent therapeutic actions.
EFFECT: method enables assessing mutual burden syndrome and effectiveness of surgical management with involving minimally invasive video-assisted endosurgical techniques.
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Authors
Dates
2011-03-27—Published
2009-06-25—Filed