COMPOSITIONS OF SACCHARIDE CONJUGATES Russian patent published in 2011 - IPC A61K39/95 A61K47/48 A61P31/04

Abstract RU 2422156 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of biotechnoloy and deals with compositions for production of vaccine against Neisseria meningitidis, which represent conjugates of different serogroups of N. meningitides with protein-carrier, selected from bacterial toxins or anatoxins, with specified size, in determination by gel-penetrating chromatography (GPC) and/or definite molecular weight in determination by exclusion chromatography with detecting by photometry of multi-angle light diffusion (SEC-MALS).

EFFECT: conjugates of claimed sizes, representing saccharide fragments, are applied in combination into polyvalent vaccine.

6 cl, 11 dwg

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RU 2 422 156 C2

Authors

Kapannoli Dzhordzho

Karinchi Valeria

D'Ashentsi Sandro

Magan'Oli Klaudia

Dates

2011-06-27—Published

2005-06-21—Filed