METHOD OF EXPERIMENTAL PROLIFERATIVE PROCESS INHIBITION IN PROSTATE TISSUE Russian patent published in 2011 - IPC G09B23/28 A61K31/565 A61P13/08 

FIELD: medicine.

SUBSTANCE: for experimental proliferative process inhibition in prostate tissues, the endoliquor introduction of the estrogenic preparation Estradurine to senior male rats in weight 200-250 g is performed. The preparation is introduced in a single dosage 0.002 mg by a suboccipital puncture. On the 10th day, the rats are decapitated for prostate examination.

EFFECT: under the conditions of the endoliquor introduction of Estradurine in specified dosages, the method provides greater proliferative activity inhibition in prostate cells, in comparison with the intramuscular introduction of estrogen, reduced synthetic activity of nucleic acids of prostate cells in the absence of weight reduction in experimental animals.