FIELD: medicine.
SUBSTANCE: suspension, containing 2 mg of 3,4-benzopyrene per 0.5 ml of 10% albumin solution and 0.5 of physiological solution, is introduced into subclavian vein of non-pedigree male rats. Suspension is obtained by ultrasonic processing, with frequency 44±4.4 kHz, with amplitude of fluctuations 30-50 mcm for 20 seconds.
EFFECT: reduction of tumour development terms with reduction of animal death at the stage of carrying out experiment, prevention of vessel embolisation due to increase of cancerogen dose as fine-dispersion carrier with improved reological properties.
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATING EXPERIMENTAL 3,4-BENZ(α)PYRENE INDUCED TUMOURS IN SPLENECTOMISED ANIMALS | 2011 |
|
RU2474430C1 |
| METHOD FOR SIMULATION OF EXPERIMENTAL MALIGNANT TUMOURS OF LUNGS | 2008 |
|
RU2375758C1 |
| METHOD OF EXPERIMENTAL PROLIFERATIVE PROCESS INHIBITION IN PROSTATE TISSUE | 2010 |
|
RU2422915C1 |
| METHOD FOR CREATING ORTHOTOPIC ENDOMETRIAL CANCER MODEL | 2024 |
|
RU2818464C1 |
| METHOD OF MODIFYING THE DEVELOPMENT OF ADENOCARCINOMA EXPERIMENTALLY | 2020 |
|
RU2743960C1 |
| METHOD FOR ENHANCING THE GROWTH OF B16/F10 MELANOMA VERSUS THE GROWTH OF B16/F10 MELANOMA WITH SELF-GRAFTING AND SLOWING THE GROWTH OF LLC (LEWIS CARCINOMA) VERSUS THE GROWTH OF LLC WITH SELF-GRAFTING IN CASE OF MULTIPLE PRIMARY MALIGNANT TUMORS AGAINST THE BACKGROUND OF PRIMARY IMMUNODEFICIENCY | 2021 |
|
RU2759487C1 |
| METHOD FOR PREVENTION OF PULMONARY METASTATIC LESIONS EXPERIMENTALLY | 2013 |
|
RU2546034C1 |
| METHOD FOR SIMULATION OF MALIGNANT PROCESS IN EXPERIMENT | 2008 |
|
RU2388064C1 |
| METHOD FOR SIMULATING LIVER METASTASES EXPERIMENTALLY | 2013 |
|
RU2538243C1 |
| METHOD FOR CREATING POLYNEOPLASIA WITH STIMULATION OF TUMOR GROWTH IN CONDITIONS OF PRIMARY IMMUNODEFICIENCY IN EXPERIMENT | 2021 |
|
RU2751930C1 |
