BIODEGRADABLE CATIONIC POLYMERS Russian patent published in 2012 - IPC C08G73/02 A61L15/42 A61F13/15 

FIELD: chemistry.

SUBSTANCE: invention relates to a cationic lypo-polymer, containing a polyethylene imine biodegradable group and a relative hydrophobic "lypo" group, or complex thereof with a biomolecule and consisting of recurring units selected from a group of formula and formula , where PEI denotes a polyethylene recurring unit; R is an electron pair; L is selected from a group consisting of C₁₂-C₁₈ fatty acids, cholesterol and derivatives thereof, C₂-C₅₀ alkyl, C₂-C₅₀ carboxyalkenyl, C₂-C₅₀ carboxyheteroalkenyl; W is a cationic part containing 2-50 carbon atoms; and m is a whole number from 1 to 30. The invention also describes methods of delivering a biomolecule to an eukaryotic cell, involving contact between the cell with said polymer.

EFFECT: obtaining polymers which can safely and effectively simplify delivery of biologically active agents to cells.

20 cl, 19 ex, 15 dwg