BORON COMPOUNDS EFFECTIVE IN BORON NEUTRON CAPTURE THERAPY Russian patent published in 2011 - IPC C07F5/02 A61K31/69 

Abstract RU 2423368 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula (I) where one of R1 and R2 represents -NH-X-Y-Z, and another represents -OH; where X represents -(CH2)m- where m is equal to 0, 1, 2, 3 or 4; Y represents carborane where at least one boron atom represents 10B; and Z represents H; and its pharmaceutically acceptable salts, solvates and stereoisomers. Also, the pharmaceutical compositions, application of the compound of formula (I) and a method of producing the compound of formula (I) are offered.

EFFECT: production of the compounds effective for boron neutron capture therapy.

15 cl, 6 ex, 3 tbl

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RU 2 423 368 C2

Authors

Ol'Sson Lars-Inge

Arzel' Ehrvan

Ehehk Arne

Dates

2011-07-10Published

2006-08-17Filed