FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing substituted 4-[cyano(phenyl)methyl]-5-nitrophthalonitriles of general formula
, where R denotes CH3, OCH3, CI, F, which can be used as semi-products in synthesis of biologically active substances, fluorescent materials and phthalocyanines. The method involves reaction of 4-bromo-5-nitrophthalonitrile with sodium salts of 2-substituted oxobutene nitriles in molar ratio 1:2, respectively, at temperature T = 19-25°C for 1-2 hours in dimethyl formamide solution, after which the reaction mass is diluted with ten-fold excess water with T = 0-25°C. The released gum residue is extracted with methylene chloride, thoroughly washed with water and chromatographed on silica gel. The eluent (solvent) is evaporated and the residue is filtered and recrystallised from alcohol.
EFFECT: method enables to obtain novel compounds of the formula given above.
5 ex
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