FIELD: pharmacology.
SUBSTANCE: group of inventions refers to a means for photodynamic therapy, which includes: 13(1)-N-{2-[N-(clozo-monocarbadodecaboron-1-yl)methyl]aminoethyl}amide-15(2),17(3)-dimethyl ester of chlorin e6: 0.047 wt %, phosphatidylcholine: 7.808 wt %, cholesterol: 1.401 wt %, DSPE-PEG-2000 - 0.129 wt %, sucrose - 11.4 wt %, DSPE-PEG (5000) Folate - 0.59 wt %, deionized water up to 100 wt %, with an allowable deviation from these values by ±5%; and also to a freeze dried powder obtained from this agent.
EFFECT: increased selectivity of agent accumulation in tumour cells and high photodynamic activity.
2 cl, 3 ex, 1 tbl, 2 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| DERIVATIVES OF 13(1)-N-{2-[N-(CLOSO-MONOCARBADODECABORAN-1-YL)- METHYL]AMINOETHYL}AMIDE-15(2),17(3)-DIMETHYL ETHER OF CHLORINE e, MANIFESTING PROPERTIES OF PHOTOSENSITISER | 2009 |
|
RU2406726C1 |
| PHARMACEUTICAL COMPOSITION CONTAINING CHLORIN E6 IN PHOSPHOLIPID NANOPARTICLES USING SPECIFIC AND PENETRATING PEPTIDES AS TARGETED MOLECULES FOR TARGETED TRANSPORT | 2020 |
|
RU2747485C1 |
| MEDICATION FOR PHOTODYNAMIC THERAPY, METHOD OF OBTAINING CLAIMED MEDICATION AND METHOD OF CARRYING OUT PHOTODYNAMIC THERAPY WITH APPLICATION OF CLAIMED MEDICATION | 2010 |
|
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| METHOD FOR PHOTODYNAMIC THERAPY OF LEFT TUMORS OF MICE EHRLICH CARCINOMA WITH CHLORINE SERIES PHOTO-SENSITIZER | 2022 |
|
RU2788766C2 |
| PHOTOSENSITISER FOR PHOTODYNAMIC THERAPY | 2013 |
|
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| METHOD FOR TREATMENT OF TRANSLABLE CONNECTIVE TISSUE SARCOMA M-1 IN RATS WITH COMBINED IMPACT OF PHOTODYNAMIC THERAPY AND RADIOTHERAPY | 2021 |
|
RU2763663C2 |
| IMMUNOLIPOSOMAL FORM OF PHOTOSENSITISER | 2009 |
|
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| PHOTOSENSITIZING AGENTS FOR PHOTODYNAMIC THERAPY | 2005 |
|
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| PHOTOSENSITIZER BASED ON THE COMPLEX OF CHLORIN E6 AND EUROPIUM | 2022 |
|
RU2797948C1 |
| METHOD OF LOW-INTENSITY LASER RADIATION DURING PHOTODYNAMIC THERAPY WITH A PHOTOSENSITIZER FOTORAN E6 OF A GRAFTED CONNECTIVE-TISSUE SARCOMA TUMOR OF M-1 RATS, POSITIVE IN A MUTANT P53 GENE | 2020 |
|
RU2736261C2 |
