ACETYLHYDRAZONE 1-CYANO-19β,28-EPOXY-2,3-SECO-18α-OLEAN-3-AL, EXHIBITING INHIBITING ACTIVITY TOWARDS VESICULAR STOMATITIS VIRUS "INDIANA" STRAIN Russian patent published in 2011 - IPC C07C243/32 A61P31/12 

Abstract RU 2429227 C1

FIELD: chemistry.

SUBSTANCE: acetylhydrazone 1-cyano-19β,28-epoxy-2,3-seco-18α-olean-3-al of formula I: has high prophylactic activity ID50 0.0001589 mcg/ml and efficiently inhibits reproduction of vesicular stomatitis virus "Indiana" strain in primarily infected cells ID50 0.21 mcg/ml.

EFFECT: high efficiency of the compounds.

3 tbl, 2 cl, 1 ex, 3 tbl

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RU 2 429 227 C1

Authors

Grishko Viktorija Viktorovna

Tolmacheva Irina Anatol'Evna

Galajko Natal'Ja Vladimirovna

Strel'Nikov Vladimir Nikolaevich

Volkova Larisa Vladimirovna

Perevozchikova Elena Nikolaevna

Pestereva Svetlana Aleksandrovna

Kaz'Janin Aleksandr Viktorovich

Dates

2011-09-20Published

2010-04-08Filed