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IPC

C07H19/73(2006-01-01)

A61K31/7068(2006-01-01)

A61P31/18(2006-01-01)

C07H13/12(2006-01-01)

(21) (22)

Application

2009149067/04, 2009-12-30

(24)

Start date

2009-12-30

(22)

Actual filing date

2009-12-30

(45)

Published

2011-09-27

(72)

Inventor

Jas'Ko Maksim VladimirovichShipitsyn Aleksandr Valer'EvichSol'Ev Pavel NikolaevichKhandazhinskaja Anastasija L'VovnaBibilashvili Robert ShalvovichVolosjuk Tat'Jana PavlovnaGolubeva Natal'Ja AleksandrovnaKononov Aleksandr Vasil'Evich

(73)

Holder

URETHANE AZT DERIVATIVES - POTENTIAL ANTIVIRAL AGENTS Russian patent published in 2011 - IPC C07H19/73 A61K31/7068 A61P31/18 C07H13/12

Abstract RU 2430103 C1

FIELD: chemistry.

SUBSTANCE: invention relates to 5'-urethane AZT derivatives of general formula

where X = -NH₂, -NHMe, -NHEt, .

EFFECT: compounds have low toxicity, can efficiently inhibit reproduction of the immunodeficiency virus type 1 virus in a CEM SS cell culture.

1 cl, 2 tbl, 7 ex

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RU 2 430 103 C1

Authors

Jas'Ko Maksim Vladimirovich

Shipitsyn Aleksandr Valer'Evich

Sol'Ev Pavel Nikolaevich

Khandazhinskaja Anastasija L'Vovna

Bibilashvili Robert Shalvovich

Volosjuk Tat'Jana Pavlovna

Golubeva Natal'Ja Aleksandrovna

Kononov Aleksandr Vasil'Evich

Dates

2011-09-27—Published

2009-12-30—Filed