FIELD: organic chemistry, virology.
SUBSTANCE: invention relates to a novel compound, namely 3'-azido-3'-deoxythymidine 5'-choline phosphate possessing antiviral activity. Indicated compound shows the enhanced penetration through cellular membranes.
EFFECT: improved and valuable property of agent.
1 tbl, 5 ex
Title | Year | Author | Number |
---|---|---|---|
DERIVATIVES OF 3'-AZIDO-3'-DEOXYTHYMIDINE 5'-H-PHOSPHONATE AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF | 2001 |
|
RU2187509C1 |
MODIFIED 5'-PHOSPHONATES OF 3'-AZIDO-3'-DEOXYTHYMIDINE AS ACTIVE COMPONENTS FOR POTENTIAL ANTIVIRAL PREPARATIONS | 2004 |
|
RU2322450C2 |
NUCLEOSIDE ANALOG PHOSPHORAMIDATES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPRODUCTION | 2003 |
|
RU2243972C1 |
URETHANE AZT DERIVATIVES - POTENTIAL ANTIVIRAL AGENTS | 2009 |
|
RU2430103C1 |
2',3'-DIDEHYDRO-2',3'-DIDEOXYTHYMIDINE-5'-[(ETHOXY-CARBONYL)(ETHYL)PHOSPHONATE] AS INHIBITOR OF REPRODUCTION OF HUMAN IMMUNODEFICIENCY VIRUS | 2000 |
|
RU2188203C2 |
NOVEL DEPOT-FORMS OF ZIDOVUDINE AND LAMIVUDINE BASED ON PHOSPHONIC ACID DERIVATIVES | 2009 |
|
RU2430104C1 |
5'-PHOSPHORUS-CONTAINING DERIVATIVES OF 2',3'-DIDEOXY-3'-THIACYTIDINE - NEW ANTIVIRAL AGENTS | 2007 |
|
RU2373218C2 |
5'-AMINOCARBONYLPHOSPHONATES D4T AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPRODUCTION | 2003 |
|
RU2247124C1 |
5'-AMINOCARBONYLPHOPHONATE 3'-AZIDO-3'-DEOXYTHYMIDINE SALTS BEING SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS HIV-1 | 2010 |
|
RU2441016C1 |
N'-{N-[3-OXO-20[29]LUPEN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPIONIC ACID ELICITING IMMUNO-STIMULATING AND ANTIVIRAL ACTIVITY | 2002 |
|
RU2211843C1 |
Authors
Dates
2007-02-20—Published
2002-07-26—Filed