NOVEL DEPOT-FORMS OF ZIDOVUDINE AND LAMIVUDINE BASED ON PHOSPHONIC ACID DERIVATIVES Russian patent published in 2011 - IPC C07H19/10 

Abstract RU 2430104 C1

FIELD: chemistry.

SUBSTANCE: invention relates to dinucleoside forms of phosphonic acids which can be used as antiviral agents, having formula where Azt is a 3'-azido-3'-deoxythymidine residue, ZTS - 2',3'-dideoxy-3'-thiacitidine residue, R is an electron acceptor group, for example ClCH2-, CH3C(O)CH2-, H2NCO-, PhCH2CH2HNCO-, PhOCH2-, CH3OCH2-, N3CH2-.

EFFECT: obtaining novel antiviral agents.

1 cl, 3 ex, 2 tbl

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RU 2 430 104 C1

Authors

Kukhanova Marina Aleksandrovna

Khandazhinskaja Anastasija L'Vovna

Shipitsyn Aleksandr Valer'Evich

Jas'Ko Maksim Vladimirovich

Bibilashvili Robert Shalvovich

Volosjuk Tat'Jana Pavlovna

Golubeva Natal'Ja Aleksandrovna

Kononov Aleksandr Vasil'Evich

Dates

2011-09-27Published

2009-12-30Filed