METHOD OF NONINVASIVE POTENTIOMETRIC DETERMINATION OF OXIDANT/ANTIOXIDANT ACTIVITY OF BIOLOGICAL TISSUES AND DEVICE FOR ITS REALISATION Russian patent published in 2011 - IPC G01N33/483 G01N27/26 

FIELD: medicine.

SUBSTANCE: invention describes method of noninvasive potentiometric determination of oxidant/antioxidant activity of biological tissues, which includes bringing analysed object in contact with electroconductive medium, which containing mediator system and estimation of oxidant/antioxidant activity by change of potential difference on electrodes, introduced into electroconductive medium, and electroconductive medium represents gel, which contains as mediator system a pair of chemical compounds, containing element in different degrees of oxidation, electrodes through gel contact with the analysed object, and oxidant/antioxidant activity is determined by formulae. For realisation of method claimed is device, which includes apparatus for measuring potential difference and filled with electroconductive medium reservoir with working electrode and electrode of comparison, connected with device for measuring potential difference, where reservoir is made open from one side. As electroconductive medium applied is gel, and working electrode is made in form of plate, placed from the side of open part of reservoir and partially covering it.

EFFECT: increase of reliability and accuracy of obtained results.

4 cl, 5 ex, 6 dwg