COMPOUND FOR SPECIFIC BINDING TO Β-AMYLOID Russian patent published in 2020 - IPC C07D277/66 C07F5/02 A61K51/04 

Abstract RU 2721845 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound which specifically binds beta-amyloid, having a structure, as shown in formula I:

formula I,

where R1 is -B(OH)2, R2 denotes -NHCH3; and boron in R1 represents 10B nuclide with a large thermal neutron capture cross section, as well as to methods for its preparation and intermediates.

EFFECT: obtaining a novel compound which specifically binds beta-amyloid, as well as visualizes beta-amyloid in PET.

12 cl, 6 dwg, 3 tbl, 5 ex

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RU 2 721 845 C2

Authors

Lyu, Yuan-Khao

Dates

2020-05-25Published

2016-12-23Filed