METHOD FOR PREDICTION OF DEVELOPING OCCUPATIONAL MALIGNANT SKIN GROWTHS IN FIBREGLASS PRODUCTION WORKERS Russian patent published in 2012 - IPC G01N33/50 C12Q1/68 

Abstract RU 2454668 C1

FIELD: medicine.

SUBSTANCE: DNA is recovered from peripheral venous blood for the purpose of analysing dup 16 polymorphism of a 3rd intervening sequence and Arg72Pro polymorphism of a 4th exon of the TP53 gene. If observing the combinations of the *Arg/*Pro and *W/*dup 16 genotypes, a risk of developing malignant skin growths is predicted. The *Arg/*Arg and *W/*W genotypes enables to predict resistance to the onset of the disease.

EFFECT: creation of the prognostic criteria of developing malignant skin growths or stability thereto in fibreglass production workers as shown by molecular-genetic markers.

3 tbl, 2 ex

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RU 2 454 668 C1

Authors

Valeeva Ehl'Vira Timer'Janovna

Bakirov Akhat Barievich

Mukhammadieva Guzel' Fanisovna

Selezneva Liana Il'Dusovna

Karimova Lilija Kazymovna

Tikhonova Tat'Jana Petrovna

Dates

2012-06-27Published

2011-04-22Filed