FIELD: biotechnologies.
SUBSTANCE: invention relates to biotechnology, particularly to dentistry and medical genetics, and can be used for prediction of malignant transformation of erosive-ulcerous Lichen Acuminatus (LICHEN) of the oral mucosa (OM). DNA is recovered from peripheral venous blood is molecular-genetic analysis of polymorphism Arg72Pro 4 Exon gene TP53. If observing the genotype Pro/Pro and allele Pro enables predicting the risk of malignant transformation of erosive-ulcerous LICHEN.
EFFECT: invention ensures production of prognostic criteria for malignant transformation of LICHEN based on molecular-genetic markers.
1 cl, 2 dwg, 3 tbl, 2 ex
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