FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed is means for prevention (prophylaxis) of liver injury in formation of syndrome of combined dystrophic-degenerative changes of mesenchimal derivatives in case of local chronic inflammatory process, located outside the liver (CDDCMD in case of LCIP located outside the liver), which represents hormone of pineal gland - melatonin and corresponding method of prevention (prophylaxis) of liver injury in formation of CDDCMD in case of LCIP.
EFFECT: invention ensures reduction of microcirculatory disorders; prevention of dystrophic changes of parenchymal cells, proliferation of connective tissue, change of structure of walls of hepatic veins vessels; prevention of increase of quantity of mast cells in surrounding of portal tract vessels; malantonin toxicity being low and side effects - minimal.
2 cl, 6 dwg, 2 tbl
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