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2 455 991

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IPC

A61K31/4468(2006-01-01)

A61K45/00(2006-01-01)

A61K31/7064(2006-01-01)

A61P11/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2011127553/15, 2011-07-05

(24)

Start date

2011-07-05

(22)

Actual filing date

2011-07-05

(45)

Published

2012-07-20

(72)

Inventor

Dygaj Aleksandr MikhajlovichSkurikhin Evgenij GermanovichAndreeva Tat'Jana ViktorovnaPershina Ol'Ga ViktorovnaKhmelevskaja Ekaterina SergeevnaErmolaeva Ljubov' Aleksandrovna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Farmakologii Sibirskogo Otdelenija Ramn

PREPARATION PREVENTING DEVELOPMENT OF ABNORMALITIES IN LUNG TISSUE UNDER CYTOSTATIC IMPACT Russian patent published in 2012 - IPC A61K31/4468 A61K45/00 A61K31/7064 A61P11/00 A61P35/00

Abstract RU 2455991 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is application of neuroleptic haloperidol as means able to prevent development of abnormalities in lung tissue, caused by introduction of cytostatics. Reduction in development of inflammatory response due to reduction of development of connective tissue (pneumofibrosis) in lungs at the background of bleomicin introduction is shown.

EFFECT: invention can be applied for pharmacological correction of abnormalities in lung tissue developing with administration of anti-tumour medications.

1 dwg, 1 tbl, 1 ex

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RU 2 455 991 C1

Authors

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Andreeva Tat'Jana Viktorovna

Pershina Ol'Ga Viktorovna

Khmelevskaja Ekaterina Sergeevna

Ermolaeva Ljubov' Aleksandrovna

Dates

2012-07-20—Published

2011-07-05—Filed