AGENT POSSESSING ANTI-INFLAMMATORY AND ANTIFIBROTIC ACTION IN PULMONARY TISSUE, AND CYTOSTATIC ACTION Russian patent published in 2014 - IPC A61K31/438 A61K31/4166 A61P11/00 A61P35/00 

Abstract RU 2530651 C1

FIELD: medicine.

SUBSTANCE: what is presented is using neuroleptic spiperone as an agent able to prevent developing disorders in pulmonary tissue caused by cytostatic bleomycin administered.

EFFECT: anti-inflammatory and antifibrotic action of spiperone is presented on simulated reversible and irreversible pulmonary fibrosis caused by bleomycin with reducing a degree of alveocyte desquamation and delaying pulmonary tissue destruction.

2 dwg, 3 tbl

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RU 2 530 651 C1

Authors

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Pershina Ol'Ga Viktorovna

Reztsova Alena Mikhajlovna

Ermakova Natalija Nikolaevna

Krupin Vjacheslav Andreevich

Khmelevskaja Ekaterina Sergeevna

Dates

2014-10-10Published

2013-11-06Filed