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2 464 983

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IPC

A61K31/451(2006-01-01)

A61K45/00(2006-01-01)

A61K31/706(2006-01-01)

A61P11/00(2006-01-01)

A61P7/06(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2011123393/15, 2011-06-08

(24)

Start date

2011-06-08

(22)

Actual filing date

2011-06-08

(45)

Published

2012-10-27

(72)

Inventor

Dygaj Aleksandr MikhajlovichSkurikhin Evgenij GermanovichAndreeva Tat'Jana ViktorovnaErmolaeva Ljubov' AleksandrovnaPershina Ol'Ga ViktorovnaKhmelevskaja Ekaterina Sergeevna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Farmakologii Sibirskogo Otdelenija Ramn

AGENT PREVENTING DEVELOPING DISORDERS IN PULMONARY TISSUE AND BLOOD SYSTEM ACCOMPANYING CYTOSTATIC ACTION Russian patent published in 2012 - IPC A61K31/451 A61K45/00 A61K31/706 A61P11/00 A61P7/06 A61P35/00

Abstract RU 2464983 C1

FIELD: medicine.

SUBSTANCE: what is offered is using cyproheptadine as an agent preventing developing disorders in pulmonary tissue and blood system caused by the introduction of cytostatics. It is shown that cyproheptadine prevents alveoli infiltration, oedema of interalveoral septum, connective tissue development in lungs with reducing blood lymphocyte count and peripheral blood and bone marrow neutrophilic granulocyte count.

EFFECT: invention may be used for pharmacological correction of pulmonary fibrosis and blood system disorders developing with prescribing anticancer preparations.

1 dwg, 1 tbl

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RU 2 464 983 C1

Authors

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Andreeva Tat'Jana Viktorovna

Ermolaeva Ljubov' Aleksandrovna

Pershina Ol'Ga Viktorovna

Khmelevskaja Ekaterina Sergeevna

Dates

2012-10-27—Published

2011-06-08—Filed