METHOD FOR IMPROVING THERAPEUTIC EFFECTIVENESS IN LUNG TISSUE DISORDERS AFTER ACTION OF CYTOSTATICS Russian patent published in 2013 - IPC A61K31/4515 A61K38/47 A61P11/00 

Abstract RU 2497523 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to therapy and pulmonology, and may be used for the purpose of the pharmacological correction of lung tissue disorders developed after the cytostatics have been prescribed. For this purpose, 3 hours after having prescribed a cytostatic, and then 1, 3, 7, 10 days thereafter, the neuroleptic agent haloperidol is administered into laboratory animals; besides every time 1 hour before administering haloperidol, hyaluronidase immobilised on polyethylene is introduced intranasally.

EFFECT: method enables the higher therapeutic effectiveness in the lung tissue disorders after the action of the cytostatics due to the manifested anti-inflammatory effect with the improved biological activity and lower toxicity and immunogenicity.

1 dwg, 1 tbl, 1 ex

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RU 2 497 523 C1

Authors

Dygaj Aleksandr Mikhajlovich

Skurikhin Evgenij Germanovich

Pershina Ol'Ga Viktorovna

Reztsova Alena Mikhajlovna

Ermakova Natalija Nikolaevna

Khmelevskaja Ekaterina Sergeevna

Krupin Vjacheslav Andreevich

Artamonov Andrej Vladimirovich

Bekarev Andrej Aleksandrovich

Kinsht Dmitrij Nikolaevich

Madonov Pavel Gennad'Evich

Reztsova Valentina Mikhajlovna

Dates

2013-11-10Published

2012-10-19Filed