METHOD OF EXAMINATION AND DIAGNOSTICS OF CONDITION OF BIOLOGICAL OBJECT OR ITS PART Russian patent published in 2012 - IPC A61B10/00 G02B21/06 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used for examination and diagnostics of biological object or its part. Method of examination and diagnostics includes the following stages: image of biological object is obtained, obtained image is calibrated and standardised, computed morphodensitometric analysis is performed. For this purpose zones of interest are identified on obtained image, required ranges of charcteristics of signal intensity are determined by fixed distribution of characteristics of irradiation interaction with substance on image, graphic presentation of distribution of intensities of image elements is formed with possibility of superposition of graphic presentation on image. After that, morphometric and densitometric parameters of image are determined, said parameters of examined object are compared with analogous parameters of reference group and decision about condition of examined object is taken on the basis of comparison results. When image of biological object is obtained, shooting of examined object is performed with additional application of illuminator with changeable emission spectrum. Source of illumination is moved on circumference around object of examination and angle of ray incidence is changed discretely at each following circle due to movement of illuminator, shooting is performed and series of object images in different spectrums of illumination for each position of illumination source is obtained, calibration of light intensity is performed in different spectrums of illumination. After that, several pictures of image are accumulated with further obtaining by said pictures average image for each version of illuminator spectrum separately, graphic presentation of distribution of intensities of image elements is performed in form of histogram. Histogram is performed with possibility of linearise and expanding in automatic, interactive modes.

EFFECT: application of claimed invention will make it possible to increase accuracy and hardness of obtained images of examined objects, and due to it obtain more objective picture of changes in biological object at the level of its structure.

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