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2 463 074

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IPC

A61K49/18(2006-01-01)

A61K33/38(2006-01-01)

A61P35/00(2006-01-01)

B82B1/00(2006-01-01)

B82Y5/00(2011-01-01)

(21) (22)

Application

2011117701/15, 2011-05-05

(24)

Start date

2011-05-05

(22)

Actual filing date

2011-05-05

(45)

Published

2012-10-10

(72)

Inventor

Khlebtsov Boris NikolaevichKhlebtsov Nikolaj Grigor'EvichTerentjuk Georgij SergeevichRumjantseva Valentina DmitrievnaIvanov Andrej Valentinovich

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Nauk Institut Biokhimii I Fiziologii Rastenij I Mikroorganizmov Ran Ran)

COMPOSITE NANOPARTICLES FOR PHOTODYNAMIC DIAGNOSIS Russian patent published in 2012 - IPC A61K49/18 A61K33/38 A61P35/00 B82B1/00 B82Y5/00

Abstract RU 2463074 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to composite nanostructures applicable for photodynamic diagnosis of malignant tumours. The declared nanostructures represent gold-silver nanocells coated by silicone dioxide formed by tetraethylortosilicate hydrolysis in an alcohol medium The silicone dioxide coating surface is functionalised by itterbium 2,4-dimethoxyhematoporfirine.

EFFECT: preparing the composite nanoparticles combining plasma resonance within biotissue transparency (760-1000 nm), fluorescence in visible and near IR spectrum, photogeneration of singlet oxygen, increased collection in new growths.

7 dwg

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RU 2 463 074 C1

Authors

Khlebtsov Boris Nikolaevich

Khlebtsov Nikolaj Grigor'Evich

Terentjuk Georgij Sergeevich

Rumjantseva Valentina Dmitrievna

Ivanov Andrej Valentinovich

Dates

2012-10-10—Published

2011-05-05—Filed