PHARMACEUTICAL COMPOSITION FOR FLUORESCENT DIAGNOSTICS OF PATHOLOGICAL CHANGES IN SKIN AND MUCOUS MEMBRANES Russian patent published in 2017 - IPC A61K31/40 

Abstract RU 2617045 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to a pharmaceutical composition for fluorescent diagnosis of pathological changes in skin and mucous membranes comprising ytterbium complex dipotassium salt of 2,4-dimethoxyhematoporphyrin IX in an amount of 0.05÷0.1 wt %, N-methylglucosamine and glycerin, and a mixture of Cremophor with DMSO at a ratio of 1:18÷20, or Tizol, or a Cremophor and Tizol mixture at a ratio of 1: 8÷10, or Kalgel as a Cremophor-containing gel base.

EFFECT: simplified process of diagnosis at diseased skin and mucous membranes; facilitated treatment monitoring; ability to identify pathological processes occurrence in the places of their localization, which can not be determined visually; significant reduction in the optimal time of pharmaceutical composition accumulation in various tumors to less than 1 hour.

3 dwg, 8 ex

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RU 2 617 045 C1

Authors

Rumyantseva Valentina Dmitrievna

Mironov Andrej Fedorovich

Chernyshev Valerij Petrovich

Shchelkunova Anastasiya Evgenevna

Ivanov Andrej Valentinovich

Shilov Igor Petrovich

Ryabov Aleksandr Sergeevich

Shumilova Natalya Maksimovna

Alekseev Yurij Vitalevich

Ponomarev Gelij Vasilevich

Dates

2017-04-19Published

2016-03-02Filed