FIELD: chemistry.
SUBSTANCE: method of producing 1-adamantylhydroperoxide of the formula given below . This compound is a semi-product in fine organic synthesis and in synthesis of certain biologically active substances. The disclosed method of producing 1-adamantylhydroperoxide involves reaction of 1,3-dehydroadamantane with hydrogen peroxide solution in diethyl ether, which is obtained by pre-extraction of hydrogen peroxide with diethyl ether from a 30% aqueous solution thereof, with subsequent drying of the ether extract over anhydrous magnesium sulphate, and the process takes place in molar ratio of reactants of 1:1.5-4, at temperature of 34-35°C for 2-3 hours, followed by separation of the end compound.
EFFECT: high output and simple method for synthesis of compounds of the disclosed structural formula.
3 ex
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Authors
Dates
2013-01-10—Published
2011-11-25—Filed