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2 759 487

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IPC

G09B23/28(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2021111455, 2021-04-22

(24)

Start date

2021-04-22

(22)

Actual filing date

2021-04-22

(45)

Published

2021-11-15

(72)

Inventor

Frantsiiants Elena MikhailovnaKaplieva Irina ViktorovnaBandovkina Valeriia AkhtiamovnaTrepitaki Lidiia KonstantinovnaSurikova Ekaterina IgorevnaPogorelova Iuliia AleksandrovnaNeskubina Irina ValerevnaKotieva Inga MovlievnaShumarin Konstantin AleksandrovichIshonina Oksana Georgievna

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Onkologii» Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

METHOD FOR ENHANCING THE GROWTH OF B16/F10 MELANOMA VERSUS THE GROWTH OF B16/F10 MELANOMA WITH SELF-GRAFTING AND SLOWING THE GROWTH OF LLC (LEWIS CARCINOMA) VERSUS THE GROWTH OF LLC WITH SELF-GRAFTING IN CASE OF MULTIPLE PRIMARY MALIGNANT TUMORS AGAINST THE BACKGROUND OF PRIMARY IMMUNODEFICIENCY Russian patent published in 2021 - IPC G09B23/28 A61P35/00

Abstract RU 2759487 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and relates to a method for enhancing the growth of B16 / F10 melanoma in comparison with the growth of B16/F10 melanoma with self-inoculation and slowing down the growth of LLC (Lewis carcinoma) compared with the growth of LLC with self-inoculation in primary multiple malignant tumors against the background of primary immunodeficiency , which consists in the fact that female mice of the BALB/cNude line are successively inoculated under the skin of the back from both sides with two tumor strains: a suspension of tumor cells B16/F10 and LLC.

EFFECT: creation of experimental model of B16/F10 and LLC growth in mice for studying the pathogenesis of multiple primary malignant tumors.

1 cl, 1 ex, 1 tbl

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RU 2 759 487 C1

Authors

Frantsiiants Elena Mikhailovna

Kaplieva Irina Viktorovna

Bandovkina Valeriia Akhtiamovna

Trepitaki Lidiia Konstantinovna

Surikova Ekaterina Igorevna

Pogorelova Iuliia Aleksandrovna

Neskubina Irina Valerevna

Kotieva Inga Movlievna

Shumarin Konstantin Aleksandrovich

Ishonina Oksana Georgievna

Dates

2021-11-15—Published

2021-04-22—Filed