FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a multidose ophthalmic composition containing prostaglandin as a therapeutic ingredient, mannitol or sorbitol 0.15-0.5 wt/vol %, propylene glycol or glycerol 0.2-1.8, borate 0.25-0.5 wt/vol %, an antimicrobial preserving agent 0.0003-0.003 wt/vol % representing a polymer quaternary ammonium compound and water. Said composition has pH 6.4-7.2 and is benzalconium chloride free. Besides, the invention refers to the use of said ophthalmic composition for preparing a drug for treating glaucoma, eye infections, allergies and inflammations.
EFFECT: preparing the ophthalmic composition which exhibits improved antimicrobial preserving activity and improved buffer properties.
16 cl, 8 tbl, 21 ex
Title | Year | Author | Number |
---|---|---|---|
AQUEOUS PHARMACEUTICAL COMPOSITIONS, CONTAINING BORATE-POLYOL COMPLEXES | 2010 |
|
RU2563125C2 |
SELF-PRESERVED WATER PHARMACEUTICAL COMPOSITIONS | 2007 |
|
RU2436568C2 |
OPHTHALMIC COMPOSITION WITH HIGH CONCENTRATION OF OLOPATADINE | 2012 |
|
RU2613715C2 |
OPHTHALMIC COMPOSITIONS WITH IMPROVED DESSICATION PROTECTION AND RETENTION | 2013 |
|
RU2659207C2 |
PHARMACEUTICAL COMPOSITION OF TAFLUPROST | 2021 |
|
RU2761625C2 |
METHODS AND COMPOSITIONS FOR TREATING PRESBYOPIA, MYDRIASIS AND OTHER OCULAR DISORDERS | 2019 |
|
RU2824137C2 |
SUSPENSIONS OF NANOPARTICLES, CONTAINING CARBOXYVINYL POLYMER | 2010 |
|
RU2571078C2 |
PHARMACEUTICAL COMPOSITION CONTAINING FLUOROQUINOLONE ANTIBIOTIC DRUG | 2009 |
|
RU2494727C2 |
OPHTHALMIC COMPOSITION WITH VISCOSITY ENHANCEMENT SYSTEM HAVING TWO DIFFERENT VISCOSITY ENHANCING AGENTS | 2012 |
|
RU2601115C2 |
PHARMACEUTICAL COMPOSITION INCLUDING DORSOLAMIDE AND BRIMONIDINE | 2017 |
|
RU2745317C2 |
Authors
Dates
2013-03-20—Published
2009-03-03—Filed