AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES Russian patent published in 2013 - IPC A61K9/08 A61K31/5575 A61K31/535 A61K47/02 A61K47/10 A61P27/02 A61P27/04 A61P7/06 A61P27/14 

Abstract RU 2477631 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a multidose ophthalmic composition containing prostaglandin as a therapeutic ingredient, mannitol or sorbitol 0.15-0.5 wt/vol %, propylene glycol or glycerol 0.2-1.8, borate 0.25-0.5 wt/vol %, an antimicrobial preserving agent 0.0003-0.003 wt/vol % representing a polymer quaternary ammonium compound and water. Said composition has pH 6.4-7.2 and is benzalconium chloride free. Besides, the invention refers to the use of said ophthalmic composition for preparing a drug for treating glaucoma, eye infections, allergies and inflammations.

EFFECT: preparing the ophthalmic composition which exhibits improved antimicrobial preserving activity and improved buffer properties.

16 cl, 8 tbl, 21 ex

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RU 2 477 631 C2

Authors

Kabra Bkhagvati P.

Dzhejni Radzhni

Dates

2013-03-20Published

2009-03-03Filed