DRUG CORES FOR DELAYED RELEASE OF THERAPEUTIC MEANS Russian patent published in 2013 - IPC A61K9/00 A61F9/00 A61F2/02 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine. Injection can be performed at temperatures, which are lower than environment temperature. Mixture is hardened to form solid core, which includes drug-matrix. Therapeutic preparation at approximately room temperature can be liquid, which forms dispersion of drops in matrix material. Surface of solid drug core is open, for instance, by means of tube cutting, and open surface of solid drug core releases therapeutic amounts of therapeutic preparations, if core is implanted into patient's organism. In some implementations body of inserted piece suppresses release of therapeutic preparation, for instance, by means of material, in fact, impermeable for therapeutic preparation, in such a way that therapeutic amounts are released through open surface, which, thus, impairs release of therapeutic preparation into tissues, at which drug action is not targeted.

EFFECT: described is solid inserted piece with drug core, which can be manufactured by means of injection of liquid mixture, which includes therapeutic preparation and initial matrix, into coating.

111 cl, 36 dwg, 13 ex