METHOD OF OBTAINING COMPOSITION OF POLYMERIC MICELLES, CONTAINING DRUG, POORLY DISSOLVED IN WATER Russian patent published in 2013 - IPC A61K9/127 A61K9/19 A61K47/30 A61K31/337 B01J13/00 A61P35/00 

Abstract RU 2478371 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: method of obtaining drug-containing composition of polymeric micelles includes: dissolution of poorly dissolved in water drug and amphiphilic block copolymer in organic solvent; and addition to obtained mixture in organic solvent of water solution with formation of polymeric micelles. Method does not require carrying out separate operation of organic solvent removal before formation of micelles. Method is simple, reduces technological time and amenable to scaling.

EFFECT: in accordance with invention method polymeric micelles preserve their stability.

14 cl, 9 tbl, 6 ex

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RU 2 478 371 C2

Authors

Seo Min Khe

Li Sa Von

Dates

2013-04-10Published

2009-06-29Filed