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(19)

(11)

2 479 576

(13)

(51)

IPC

C07D209/08(2006-01-01)

C07D401/06(2006-01-01)

C07D407/06(2006-01-01)

C07D417/06(2006-01-01)

C07D417/10(2006-01-01)

A61K31/40(2006-01-01)

A61K31/404(2006-01-01)

A61P13/00(2006-01-01)

(21) (22)

Application

2010150911/04, 2009-05-12

(24)

Start date

2009-05-12

(22)

Actual filing date

2009-05-12

(45)

Published

2013-04-20

(72)

Inventor

Nozava EhjsukeIbuka RiotaroIkegai KazukhiroMatsuura KejsukeZenkokh TatsujaSeo RjusiVatanuki SusumuKagejama Mitikhito

(73)

Holder

Astellas Farma Ink.

AMIDE COMPOUND Russian patent published in 2013 - IPC C07D209/08 C07D401/06 C07D407/06 C07D417/06 C07D417/10 A61K31/40 A61K31/404 A61P13/00

Abstract RU 2479576 C9

FIELD: chemistry.

SUBSTANCE: compounds exhibit antagonistic activity towards the EP4 receptor, which enables use thereof as an active ingredient in a pharmaceutical composition for treating chronic kidney disease or diabetic nephropathy.

EFFECT: high efficiency of the compounds.

27 cl, 228 tbl, 86 ex

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RU 2 479 576 C9

Authors

Nozava Ehjsuke

Ibuka Riotaro

Ikegai Kazukhiro

Matsuura Kejsuke

Zenkokh Tatsuja

Seo Rjusi

Vatanuki Susumu

Kagejama Mitikhito

Dates

2013-04-20—Published

2009-05-12—Filed