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2 480 843

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(51)

IPC

G09B23/28(2006-01-01)

(21) (22)

Application

2011148067/14, 2011-11-18

(24)

Start date

2011-11-18

(22)

Actual filing date

2011-11-18

(45)

Published

2013-04-27

(72)

Inventor

Netyl'Ko Georgij IvanovichNakonechnyj Dmitrij GeorgievichRumakin Vasilij PetrovichZajtseva Marina Jur'EvnaBozhko Aleksej MikhajlovichKonev Vladimir Aleksandrovich

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Ordena Trudovogo Krasnogo Znameni Nauchno-Issledovatel'Skij Institut Travmatologii I Ortopedii Im. R.R. Vredena" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii Im. R.R. Vredena" Minzdravsotsrazvitija Rossii)

METHOD FOR CREATING EXPERIMENTAL MODEL OF OSTEOPOROSIS IN RABBIT Russian patent published in 2013 - IPC G09B23/28

Abstract RU 2480843 C1

FIELD: medicine.

SUBSTANCE: modelling in rabbits is performed by one-side ovarioectomy and introduction of hydrocortisone 3 days later. Hydrocortisone is injected under the regimen: 1^st, 14^th days 0.1 ml (mg); 2^nd, 3^rd, 12^th, 13^th days - 0.2 ml (mg); 4^th-11^th days 0.3 ml (mg).

EFFECT: method provides creating an adequate model of osteoporosis with decreased mortality rate in experimental animals and manifestations of hormone withdrawal syndrome.

2 dwg

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RU 2 480 843 C1

Authors

Netyl'Ko Georgij Ivanovich

Nakonechnyj Dmitrij Georgievich

Rumakin Vasilij Petrovich

Zajtseva Marina Jur'Evna

Bozhko Aleksej Mikhajlovich

Konev Vladimir Aleksandrovich

Dates

2013-04-27—Published

2011-11-18—Filed