NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND Russian patent published in 2013 - IPC C07D207/34 C07D403/12 C07D413/12 C07D413/14 C07D417/12 C07D417/14 A61K31/40 A61K31/4155 A61K31/4178 A61K31/42 A61K31/422 A61K31/4245 A61K31/427 A61K31/4439 A61P3/06 A61P3/10 A61P9/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to compounds of general formula (I), wherein A represents a pyrrole group or a pyrazole group, and X represents a carbon atom or a nitrogen atom; R¹ represents a carboxy group; R² independently represents a group specified in a substitute group α; R³ independently represents phenyl(C₁-C₆alkyl)group substituted by, phenyl(C₁-C₆alkyl)group (wherein the substitute(s) represents (represent) 1-4 groups independently specified in the substitute group α); m is equal to 0, 1, 2 or 3, n is equal to 0 or 1; each of R⁴, R⁵, R⁶ and R⁷ independently represents a hydrogen atom, C₁-C₆alkyl group or a halogen atom; B represents a substituted naphthyl group (wherein the substitute(s) represents (represent) 1-4 groups independently specified in the substitute group α), or the group represented by formula (II), wherein B¹, B² and α are those as specified in the patent claim. Also, the invention refers to a pharmaceutical composition possessing lipolysis inhibiting activity, to the use of the compounds of formula (I) in preparing a drug preparation for treating hyperlipidemia, dislipidemia, abnormal lipid metabolism, arteriosclerosis or type II diabetes mellitus and to a method of treating or preventing the mentioned diseases.

EFFECT: preparing the compounds of formula (I) possessing lipolysis inhibiting activity.

36 cl, 1 dwg, 1 tbl, 69 ex