METHOD FOR DETECTING EARLY SIGNS OF CHRONIC EXPOSURE TO VINYL CHLORIDE Russian patent published in 2013 - IPC G01N33/50 

FIELD: medicine.

SUBSTANCE: workers' blood serum is analysed for interleukin 4, protein S-100β, protein S-100 autoantibodies, voltage-dependent Ca-channel autoantibodies, glutamate receptor autoantibodies, γ-aminobutyrate receptor autoantibodies, dopamine receptor autoantibodies; diagnostic coefficients F₁ and F₂ are calculated; if the value F₁ is less than F₂, the early changes of the nervous system are diagnosed for the chronic exposure to vinyl chloride; F₁ more or equal to F₂ enables stating the absence of any signs of the chronic exposure to vinyl chloride. The developed method may be used in the periodic medical screenings, medical examinations of workers to diagnose some occupational diseases.

EFFECT: use of the invention improves higher accuracy of identifying the various signs of the chronic exposure to vinyl chloride through the use of a complex of the immunological structures of nerve tissue in the chronic exposure to vinyl chloride.

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