Show metadata Hide metadata

(19)

(11)

2 486 182

(13)

(51)

IPC

C07D409/14(2006-01-01)

A61K31/404(2006-01-01)

A61K31/4535(2006-01-01)

A61K31/454(2006-01-01)

A61P7/02(2006-01-01)

(21) (22)

Application

2011131915/04, 2011-07-28

(24)

Start date

2011-07-28

(22)

Actual filing date

2011-07-28

(45)

Published

2013-06-27

(72)

Inventor

Spasov Aleksandr AlekseevichSuzdalev Konstantin FilippovichKucherjavenko Aida FatikhovnaPetrov Vladimir IvanovichMinkin Vladimir Isaakovich

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii"

DRUG PREPARATION POSSESSING ANTIAGGRREGANT ACTIVITY Russian patent published in 2013 - IPC C07D409/14 A61K31/404 A61K31/4535 A61K31/454 A61P7/02

Abstract RU 2486182 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a biologically active substance possessing the antiaggregant properties. The technical effect: what is produced is a drug preparation of a new compound of (2E)-3-[1-(2-hydroxy-3-piperidin-1-ylpropyl)-1 H-indol-3-yl]-1-(2-thienyl)prop-2-en-1-one hydrochloride of formula I possessing antiaggregant action:

EFFECT: substance may be used in medicine for producing a drug preparation for preventing the conditions associated with a high thrombogenic potential of blood.

1 cl, 2 tbl, 1 ex

Similar patents RU2486182C2

Title	Year	Author	Number
2-PIPERIDINO-5-(THIENYL-2)- AND 2-PIPERIDINO-5-(THIENYL-3)- 6H-1,3,4-THIADIAZINES HYDROBROMIDES POSSESSING ANTIAGGREGANT ACTION	2010	Chupakhin Oleg Nikolaevich Sidorova Larisa Petrovna Perova Natal'Ja Mikhajlovna Rusinov Vladimir Leonidovich Makarov Vladimir Aleksandrovich Vasil'Eva Tat'Jana Mikhajlovna	RU2445310C2
HYDROHALOGENIDES 3-[1-(2-HYDROXY-3-PIPERIDINE-1-YL-PROPYL)-1H-INDOLE-3-YL]-1-PHENYL-PROPENONE, HAVING LOCAL ANAESTHETISING AND ANTI-ARRHYTHMIC ACTIVITY	2008	Suzdalev Konstantin Filippovich Den'Kina Sof'Ja Vladimirovna Galenko-Jaroshevskij Pavel Aleksandrovich Varlashkina Inessa Aleksandrovna Cherednik Irina Leonidovna Shejkh-Zade Jurij Reshadovich Taran Oksana Anatol'Evna Takhchidi Khristo Periklovich Sakhnov Sergej Nikolaevich Dol'Skaja Oksana Aleksandrovna Lisitsyna Nadezhda Pavlovna Bguasheva Behlla Askerovna Bogus Saida Kazbekovna	RU2408592C2
2-CYCLOALKYLAMINO-5-THIENYL-1,3,4-THIADIAZINES, HYDROBROMIDES, WITH ANTIAGGREGANT ACTIVITY	2008	Chupakhin Oleg Nikolaevich Sidorova Larisa Petrovna Perova Natal'Ja Mikhajlovna Rusinov Vladimir Leonidovich Makarov Vladimir Aleksandrovich Vasil'Eva Tat'Jana Mikhajlovna Vorob'Ev Andrej Ivanovich	RU2379306C1
1-SUBSTITUTED-3-{[2-(3,5-DI-TRET-4-HYDROXYPHENYL)-2-OXOETHYL]}-2AMINOBENZIMIDAZOLIUM BROMIDES WITH ANTIPLATELET AND ANTIOXIDANT PROPERTIES	2016	Anisimova Vera Alekseevna Zhukovskaya Olga Nikolaevna Petrov Vladimir Ivanovich Spasov Aleksandr Alekseevich Kosolapov Vadim Anatolevich Kucheryavenko Aida Fatikhovna Gajdukova Kseniya Andreevna Sorotskij Dmitrij Vladimirovich	RU2623439C1
AGENT SHOWING ANTIAGGREGANT AND ANTITHROMBOGENIC ACTIVITY	2010	Spasov Aleksandr Alekseevich Anisimova Vera Alekseevna Petrov Vladimir Ivanovich Kucherjavenko Aida Fatikhovna Tolpygin Ivan Evgen'Evich Minkin Vladimir Isaakovich	RU2453312C1
2-(2-OXOINDOLIN-3-YLIDENE)METHYL-5-(2-HYDROXY-3-MORPHOLIN-4-YLPROPYL)-6,7-DIHYDRO-1-H-PYRROLE[3,2-C]PYRIDIN-4(5H)-ONE COMPOUNDS AND USE THEREOF AS PROTEIN KINASE INHIBITORS	2008	Tan Pehn Chzho Jan Tszjaljan Su Idun Chzhao Futsjan	RU2472792C2
AGENT EXHIBITING ANTIAGGREGATORY ACTIVITY	2019	Urakov Aleksandr Livievich Samorodov Aleksandr Vladimirovich Bashirova Linara Irekovna Urakova Natalya Aleksandrovna Purygin Petr Petrovich Ermokhin Vladimir Anatolevich Bondareva Nataliya Aleksandrovna	RU2727508C1
USE OF 2,3,4-TRIMETHOXY-5-HYDROXY-9,10-DIHYDROPHENANTHRENE AS AN AGENT WITH ANTI-AGGREGATION ACTIVITY	2023	Luzhanin Vladimir Gennadevich Ueili Andrei Kennet Ueili Anastasiia Olegovna Samorodov Aleksandr Vladimirovich	RU2808460C1
5-(4'-HYDROXYPHENYL)-AND 5-(2',5'-DIHYDROXYPHENYL)-6 H-1,3,4-THIADIAZINE-2-AMINES, HYDROHALOGENIDES INHIBITING THROMBOCYTE AGGREGATION IN INTRAVENOUS INTRODUCTION	2009	Chupakhin Oleg Nikolaevich Sidorova Larisa Petrovna Petrova Natal'Ja Mikhajlovna Novikova Antonina Petrovna Rusinov Vladimir Leonidovich Makarov Vladimir Aleksandrovich Vasil'Eva Tat'Jana Mikhajlovna	RU2458060C2
N-[(1H-PYRAZOL-1-YL) ARYL]-1H-INDOLE OR 1H-INDAZOLE-3-CARBOXAMIDE DERIVATIVES, PRODUCING AND USING THEM AS P2Y12 ANTAGONISTS	2011	Badork Alan Boldron Kristof Delesk Natali Fossi Valeri Lassall' Zhil'Ber Ivon Ksav'E	RU2572593C2

RU 2 486 182 C2

Authors

Spasov Aleksandr Alekseevich

Suzdalev Konstantin Filippovich

Kucherjavenko Aida Fatikhovna

Petrov Vladimir Ivanovich

Minkin Vladimir Isaakovich

Dates

2013-06-27—Published

2011-07-28—Filed